• Acitretin

Acitretin

  • CasNo:55079-83-9
  • Purity:99%

Product Details;

CasNo: 55079-83-9

Molecular Formula: C21H26O3

Appearance: crystalline solid

We supply high quality Acitretin (CAS 55079-83-9), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Acitretin ?

Acitretin is crystalline solid, while it's Molecular Formula is C21H26O3. Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.

What is the CAS number for Acitretin ?

The CAS number of Acitretin is 55079-83-9.

More information of Acitretin 55079-83-9 are:

Synonyms

(all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid;all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid;Neotigason;2,4,6,8-Nonatetraenoic acid,9-(4-methoxy-2,3,6-trimethylphenyl)-3,- 7-dimethyl-,(2E,4E,6E,8E)-;Etretin;Acitretinum [Latin];Acitretina [Spanish];all-trans-Acitretin;Acitretine [French];Acitretin [USAN:BAN:INN];Soriatane;2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-, (all-E)-;

CAS Number

55079-83-9

Molecular Formula

C21H26O3

Molecular Weight

326.436

Density

1.051 g/cm3

Melting Point

228-230 °C

Boiling Point

521.3 °C at 760 mmHg

Flash Point

180.3 °C

HS CODE

2918992090

PSA

46.53000

LogP

5.16700

Pka

4.72±0.33(Predicted)

What is Acitretin (55079-83-9) used for?

Acitretin is the free acid form of etretinate useful in the treatment of severe psoriasis and other disorders of keratinization. Although the two compounds have virtually the same efficacy and teratogenic side-effects, acitretin is advantageous for child-bearing women, as its shorter half-life reduces the necessary contraception period from two years to only one month after treatment ceases.

InChI:InChI=1/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12-

Articles related to Acitretin:

Article

Source

Dual Nickel/Ruthenium Strategy for Photoinduced Decarboxylative Cross-Coupling of α,β-Unsaturated Carboxylic Acids with Cycloketone Oxime Esters

Gao, Ang,Jiang, Run-Chuang,Liu, Chuang-Chuang,Liu, Qi-Le,Lu, Xiao-Yu,Xia, Ze-Jie

, p. 8829 - 8842 (2021/06/30)

PROCESS FOR PREPARATION OF ACITRETIN

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Page/Page column 11, (2016/04/20)

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