CasNo: 55079-83-9
Molecular Formula: C21H26O3
Appearance: crystalline solid
We supply high quality Acitretin (CAS 55079-83-9), in stock, factory directly supply to clients, lower prices, more competitiveness.
Acitretin is crystalline solid, while it's Molecular Formula is C21H26O3. Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.
The CAS number of Acitretin is 55079-83-9.
More information of Acitretin 55079-83-9 are:
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Synonyms |
(all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid;all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid;Neotigason;2,4,6,8-Nonatetraenoic acid,9-(4-methoxy-2,3,6-trimethylphenyl)-3,- 7-dimethyl-,(2E,4E,6E,8E)-;Etretin;Acitretinum [Latin];Acitretina [Spanish];all-trans-Acitretin;Acitretine [French];Acitretin [USAN:BAN:INN];Soriatane;2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-, (all-E)-; |
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CAS Number |
55079-83-9 |
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Molecular Formula |
C21H26O3 |
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Molecular Weight |
326.436 |
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Density |
1.051 g/cm3 |
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Melting Point |
228-230 °C |
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Boiling Point |
521.3 °C at 760 mmHg |
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Flash Point |
180.3 °C |
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HS CODE |
2918992090 |
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PSA |
46.53000 |
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LogP |
5.16700 |
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Pka |
4.72±0.33(Predicted) |
Acitretin is the free acid form of etretinate useful in the treatment of severe psoriasis and other disorders of keratinization. Although the two compounds have virtually the same efficacy and teratogenic side-effects, acitretin is advantageous for child-bearing women, as its shorter half-life reduces the necessary contraception period from two years to only one month after treatment ceases.
InChI:InChI=1/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12-
Articles related to Acitretin:
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Article |
Source |
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Dual Nickel/Ruthenium Strategy for Photoinduced Decarboxylative Cross-Coupling of α,β-Unsaturated Carboxylic Acids with Cycloketone Oxime Esters |
Gao, Ang,Jiang, Run-Chuang,Liu, Chuang-Chuang,Liu, Qi-Le,Lu, Xiao-Yu,Xia, Ze-Jie , p. 8829 - 8842 (2021/06/30) |
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PROCESS FOR PREPARATION OF ACITRETIN |
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