We supply high quality Hydroxychloroquine sulfate (CAS 747-36-4), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the Hydroxychloroquine sulfate ?
Hydroxychloroquine sulfate is White cyrstalline solid, while it's Molecular Formula is C18H26ClN3O*H2O4S. antimalarial, lupus suppressant
What is the CAS number for Hydroxychloroquine sulfate ?
The CAS number of Hydroxychloroquine sulfate is 747-36-4.
More information of Hydroxychloroquine sulfate 747-36-4 are:
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Synonyms
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Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt) (8CI);Plaquenil;Hydroxychloroquine sulfate (USP);Hidroxicloroquina [INN-Spanish];Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-, sulfate (1:1);Ercoquin;Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, monosulfate;Toremonil;2-((4-((7-Chloro-4-quinolinyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt);Idrossiclorochina [DCIT];Ethanol, 2-[[4-[ (7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt);Ethanol,2-[[4-[(7-chloro-4-quinolinyl)amino]- pentyl]ethylamino]-,sulfate (1:1) (salt);Plaquinol;Hydroxychloroquinum [INN-Latin];Hydroxychloroquine sulphate;Plaquenil sulfate;Plaquenil (TN);HCQ;2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethyl-amino]ethanol; sulfuric acid;Ethanol, 2-[[4-[ (7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt);Hydroxy Chloroquine Sulphate;Hydroxychloroquine-Sulphate; |
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CAS Number
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747-36-4 |
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Molecular Formula
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C18H26ClN3O*H2O4S |
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Molecular Weight
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433.956 |
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Melting Point
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240 °C |
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Boiling Point
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516.7 °C at 760 mmHg |
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Flash Point
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266.3 °C |
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HS CODE
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29334990 |
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PSA
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131.37000 |
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LogP
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4.28400 |
What is Hydroxychloroquine sulfate (747-36-4) used for?
Hydroxychloroquine is an aminoquinoline with antimalarial, anti-inflammatory, and antiviral activities. It is active against the chloroquine-sensitive NF54 and D6 strains of P. falciparum (IC50s = 16.3 and 15 nM, respectively) but has decreased activity against chloroquine-resistant P. falciparum strains (IC50s = 422.7-1,735.3 nM). Hydroxychloroquine inhibits production of IL-22, IL-17A, and IL-6 induced by phorbol 12-myristate 13-acetate (TPA; ) and ionomycin in peripheral blood mononuclear cells (PBMCs) isolated from healthy individuals or patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA). It inhibits accumulation of sequestosome-1 (SQSTM1) puncta, a marker of autophagy, in mouse embryonic fibroblasts (MEFs) in a concentration-dependent manner. Hydroxychloroquine reduces viral titers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the culture supernatant of infected Vero E6 cells but does not reduce SARS-CoV-2 viral titers in an in vitro human airway epithelium model or the respiratory tract of infected cynomolgus macaques. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of RA and SLE.
InChI:InChI=1/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/p+2/t14-/m0/s1
Articles related to Hydroxychloroquine sulfate:
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Article
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Source
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Synthesis and evaluation of enantiomers of hydroxychloroquine against SARS-CoV-2 in vitro
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Ni, Yong,Liao, Jinbiao,Qian, Zhenlong,Wu, Chunxiu,Zhang, Xiangyu,Zhang, Ji,Xie, Youhua,Jiang, Sheng
, (2021/12/08)
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Hydroxychloroquine sulfate crystal form B and preparation method thereof
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Paragraph 0035-0036, (2021/03/13)
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How to get the best price on Hydroxychloroquine sulfate?
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